Infinitus Systems

Overview

Infinitus Systems is a San Francisco-based AI company founded in 2019 by Ankit Jain (CEO) and Shyam Rajagopalan (CTO), built on a single insight: the same conversational AI that Google Duplex used to book restaurant reservations could be far more valuably deployed automating the administrative phone calls that throttle U.S. healthcare. The company automates outbound calls from healthcare organizations — pharmaceutical manufacturers, specialty pharmacies, provider groups, health systems — to insurance payers, collecting benefit verification data, prior authorization status, formulary exception details, claims information, and more. Where a human reimbursement specialist might spend 35-45 minutes on hold and navigating IVRs to extract a single set of eligibility data, an Infinitus AI agent handles the same call end-to-end and returns structured data through an API.

The founding story: in 2018, Jain was working as Director of Engineering in Google’s AI division and managing Gradient Ventures (Google’s AI-focused seed fund) when he watched Google I/O’s Duplex demo. His wife Shailvi — a healthcare professional — challenged him to apply the technology to healthcare’s administrative nightmare rather than dinner reservations. Jain recruited Rajagopalan (ex-Snap security engineering) and the company made its first automated call in 2019, initially using a deliberately robotic-sounding voice named “Eva” to make clear to payer agents they were speaking with a machine.

Key facts: 340 Brannan Street, San Francisco. Total funding $102.9M across four rounds. Valuation ~$600M (October 2024, per Bloomberg). ~193 employees (2024). Backers: Andreessen Horowitz, Kleiner Perkins, Coatue, GV (Google Ventures), Memorial Hermann Health System. Compliance: HIPAA, SOC 2 Type 2, HITRUST Certified Cloud.

Services & Capabilities

Core Product: AI Voice Agents (Payer-Facing)

Infinitus’s flagship capability is fully autonomous outbound voice AI that calls insurance payers on behalf of healthcare customers. The AI agent navigates IVR phone trees, waits on hold, conducts live conversations with payer representatives, and returns structured data via API — all without human intervention in the standard workflow. As of late 2024, the platform had automated over 4 million calls with an average call length of 34.5 minutes, and by April 2025 had crossed 100 million minutes of healthcare conversations and 6 million total calls automated.

Payer-facing use cases include:

• Benefit verification — plan details, deductibles, out-of-pocket maximums, drug and admin coverage, coordination of benefits, network status, specialty pharmacy requirements, buy-and-bill availability
• Prior authorization — PA requirements, current status (pending/approved/denied/canceled), denial reasons, appeal options, bridge eligibility re-verification
• Prior authorization follow-up — automated polling at preset intervals until PA decision received
• Claims status — real-time claims tracking
• Formulary exception — submission process, follow-up, outcome
• Insurance discovery — identifying a patient’s active coverage when plan details are unknown
• Medicare Part B / MBI lookup — electronic eligibility for government plans

A single call may require collecting over 200 distinct data outputs. The longest call documented ran 3 hours and 15 minutes with 306 conversational turns.

FastTrack (AI Copilot)

Launched October 2024, FastTrack is a human-in-the-loop copilot for reimbursement specialists. Rather than fully automating a call, FastTrack handles IVR navigation and hold time, then drops the human specialist into the conversation once a live payer agent picks up. Auto-generates call summary notes. Hundreds of users reported an average 25% productivity increase. Integrations include Salesforce Life Sciences Cloud and Epic via SMART on FHIR.

Patient- and Provider-Facing AI Agents

Launched April 2025 with “hallucination-free” discrete action space architecture:

• Patient agents: proactive medication adherence check-ins, side effect escalation, health risk assessments, around-the-clock patient Q&A, income verification for subsidy programs
• Provider agents: clinical documentation follow-up, provider education on treatment policies, signature collection

Agentic AI Member Services Suite (Health Plans)

Launched February 2026 for payers — intelligent IVR replacement, member onboarding, care navigation. A strategic expansion into health plan member services.

Technology Platform

Infinitus uses a “multimodal, multi-model” architecture — an ensemble of 100+ models ranging from lightweight models (dozens of parameters) to mid-size custom healthcare audio/text models (~100M parameters) to frontier LLMs (up to 10T parameters, including fine-tuned Gemini and GPT-4o). Three foundational components:

1. Proprietary knowledge graph — continuously updated from 7M+ automated calls, direct payer API integrations, electronic eligibility transactions, and official coverage policy documents. Determines plan category, IVR navigation paths, payer-specific call procedures, and real-time coverage rules. Updated daily via rule-mining algorithms.

2. Discrete action space / coordination layer — proprietary architecture sitting on top of LLMs to prevent hallucination by restricting the agent to a predefined action space of approved conversation flows. This is Infinitus’s primary differentiator on trust and compliance.

3. AI review system — automated post-call quality layer combining LLM-generated features with XGBoost classifiers trained on historical human reviewer data, producing explainable predictions that flag calls for redo or human correction.

Integrations: Salesforce Health Cloud/Life Sciences Cloud (Agentforce + MuleSoft), SMART on FHIR for EHR launch (Epic), Google Cloud Vertex AI, MCP/A2A agent interoperability protocols, IBM Consulting partnership.

Published performance: 98% call success rate, 10% greater data accuracy vs. human callers, 100+ FTE offset at Cencora, 50% more patients served at Mercalis.

Competitive Position

Infinitus is the clear market leader among AI voice PA companies by every metric: funding ($102.9M), scale (100M+ conversation minutes, 6M+ calls), enterprise penetration (44% of Fortune 50 healthcare companies), and breadth of pharma-specific capabilities.

vs. SuperDial: The most direct product competitor. SuperDial targets RCM billing companies and provider organizations (DSOs, MSOs), whereas Infinitus’s largest customers are pharmaceutical manufacturers and specialty pharmacies. SuperDial maintains a human call center for failed calls (more accessible to customers not ready for full autonomy); Infinitus pursues end-to-end automation with human review only post-call. Infinitus’s 4-year head start, $600M valuation vs. SuperDial’s ~$20M post-money, and Fortune 50 customer base represent a commanding scale gap.

vs. Coral AI: Not primarily a phone automation company. Coral automates document-based workflows (faxes, referral packets, PA submission via portals). Competes more with Waystar and Cohere Health.

vs. CoverMyMeds: Complementary, not competitive. CoverMyMeds handles electronic PA submission (provider-to-payer digital routing); Infinitus handles PA status verification and benefits investigation by phone.

The broader moat: Every call feeds the knowledge graph. 7M+ calls of payer IVR navigation, hold patterns, representative phrasing, and coverage rules creates a compounding data advantage. Dedicated payer phone lines at major insurers create bilateral dependency.

Recent Developments

• October 2024: Series C ($51.5M) led by a16z at ~$600M valuation; FastTrack AI copilot GA; named CB Insights Digital Health 50
• March 2025: Named to Fast Company’s World’s Most Innovative Companies (Healthcare)
• March 2025: Launched dedicated PA follow-up automation — “the only company to offer automation of prior authorization call tasks” end-to-end
• April 2025: Launched patient-facing and provider-facing voice AI agents with Zing Health as anchor customer
• June 2025: Expanded Salesforce partnership — native Managed Package for Health Cloud and Life Sciences Cloud; Agentforce and MuleSoft connectors
• September 2025: IBM Consulting partnership for specialty pharmacy AI at scale — 60,000+ tasks completed in H1 2025 for one specialty pharmacy, saving 29 minutes per BV call
• October 2025: Outshift by Cisco partnership on multi-agent interoperability; contributed to AGNTCY open-source framework (Linux Foundation)
• November 2025: Addressed payer-blocking issue publicly — distinguished itself through dedicated payer lines, transparent call volume planning, and digital-first data collection
• February 2026: Launched Agentic AI Member Services Suite for health plans

Financial Profile

Metric	Value
Total Funding Raised	$102.9M
Seed	Kleiner Perkins-led (undisclosed)
Series A (Feb 2021)	$21.4M — Kleiner Perkins, Coatue, Gradient Ventures
Series B (Nov 2021)	$30M — GV (lead), Kleiner Perkins, Coatue
Series C (Oct 2024)	$51.5M — a16z (lead), Memorial Hermann, existing investors
Post-money valuation (Oct 2024)	~$600M
Estimated ARR (2024)	~$26-30M (third-party estimates; unverified)
Revenue Growth (2022-2024)	298% over 24 months (CEO-disclosed)
Employees	~170-195
Key Investors	a16z (board seat: Scott Kupor), GV, Kleiner Perkins, Coatue, Memorial Hermann

Revenue model is usage-driven SaaS: platform/license fees plus per-call/per-task pricing. Meaningful gross margin leverage as the knowledge graph matures — accumulated payer intelligence serves all customers without proportional cost growth.

Client Types

(1) Pharma manufacturers with patient access/hub programs (44% of Fortune 50, including Amgen, GSK, Novartis); (2) Hub operators/life sciences commercialization (Cencora, Mercalis/TrialCard, Neovance); (3) Specialty pharmacies processing high volumes of BV and PA; (4) Health systems/ambulatory surgery centers (Gramercy Surgery Center); (5) Payors (Zing Health for Medicare Advantage member services).

Sources

• Infinitus.ai, Series C PR (Oct 2024), TechCrunch (Feb 2021), Bloomberg valuation (Oct 2024), April 2025 trusted AI agents (PR Newswire), Pulse 2.0 CEO interview, Fast Company 2025, Payer-blocking blog (Nov 2025), Agentic AI Suite (Feb 2026)
• Perplexity Wave 2 Agent 17 enrichment (raw/research/02_infinitus_systems.md)